Natural history of hepatitis C virus infection

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[Natural history of hepatitis C virus infection].

Over 70% of individuals acutely infected with hepatitis C virus (HCV) develop chronic infection at significant risk of progressive liver fibrosis and subsequent liver cirrhosis and hepatocellular carcinoma. Various viral, host, and environmental factors have been reported to affect the natural history of HCV infection such as chronicity in acute phase and disease progression in chronic phase. R...

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Natural history of hepatitis C virus infection

The natural history of hepatitis C virus infection is still unclear. This disease has a long clinical latency period and very frequently develops into chronic forms (in 70-80% of cases). Diagnosis of chronic HCV infection can only be based on liver biopsy. Histological scores permit rating disease severity and to compare successive biopsy specimens. Certain clinical peculiarities deserve to be ...

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The natural history of hepatitis C virus infection.

The natural history of HCV infection remains ill-defined. The knowledge accumulated on the progression of HCV to date is important, however. It is now abundantly clear that the progression of disease is generally slow, and the development of cirrhosis and its complications is a possibility, not a probability as hitherto thought. Predicting the outcome remains a quandary for clinicians. Ultimate...

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Epidemiology and natural history of hepatitis C virus infection.

Hepatitis C virus (HCV) affects 130-210 million people worldwide and is one of the major risk factors for hepatocellular carcinoma. Globally, at least one third of hepatocellular carcinoma cases are attributed to HCV infection, and 350000 people died from HCV related diseases per year. There is a great geographical variation of HCV infection globally, with risk factors for the HCV infection dif...

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The Natural History of Hepatitis C Virus (HCV) Infection

Hepatitis C virus (HCV) is a leading cause of chronic liver disease, cirrhosis, and hepatocellular carcinoma, as well as the most common indication for liver transplantation in many countries. Although the incidence of hepatitis C infection has dramatically decreased during the past decade, the worldwide reservoir of chronically infected persons is estimated at 170 million, or 3% of the global ...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 1996

ISSN: 0931-0509,1460-2385

DOI: 10.1093/ndt/11.supp4.16